What is the main symptom of Hodgkin's disease?

• A. Fever
• B. Pain
• C. Enlarged Lymph Nodes
• D. Weight Loss

Answer: (C)

Painless enlargement of lymph nodes is the hallmark feature being tested. Hodgkin lymphoma typically begins with swollen, non-tender nodes, often in the neck or above the collarbone, due to malignant lymphoid tissue proliferation. While systemic symptoms like fever, night sweats, and weight loss can occur (these are called B symptoms), they are not the most common presenting sign. Painful nodes or pain triggered by alcohol are not typical initial findings. So the best answer reflects the frequent first clue: enlarged lymph nodes.